<p>
On April 11, 1677 (according to Concepcion's account from his Hist. de Philipinas, vii, pp. 258, 259), Governor Manuel de Leon died due to excessive obesity.  De Leon left all his property for charitable purposes.
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<p>
Casimiro Diaz from his Conquistas said that Governor General Manuel de Leon died on the night of April 8, 1676.  
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<p>
Below is a direct extract of Diaz  account in Pages 157-161 of The Philippine Islands, 1493-1898 Volume XLII, (1670-1700), edited by Blair,  on how de Leon died:
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<div class="source-notes">
<div class="book-extract-ear">
<p>
At this time, in the year 1675, Governor Don Manuel de León was in great danger of dying, on account of having placed himself under medical treatment, 

without being actually sick, solely for the sake of improving his health—a proof that it might have cost him his life. Don Manuel was a corpulent man, 

and had grown so fleshy that he was almost unable to move about without aid, at which he grieved much because he could not attend to many functions 

which belonged to the obligations of his office. In view of this hindrance and his desires, Juan Ventura Sarra (whom I have already mentioned in the 

voyages to Siam and the coast of Coromandel) bound himself to cure Don Manuel and remove from him that great encumbrance [of flesh]—confident because 

he was a very expert surgeon, and the governor a man of great courage and reared in and accustomed to the perils of war. The governor accordingly 

accepted this treatment; and the skillful surgeon opened his abdomen in many places and removed from him many lumps of fat, and then sewed up and 

treated the wounds. In a few weeks the governor became well, and his flesh was much reduced, to the wonder of those who saw how the surgeon cut the 

flesh from his body, and the courage which the governor displayed—and what caused most dread [of the result] was his being an aged man, but little 

less than seventy years old. The king of León, Don Sancho I, was cured about the year 920 of a similar infirmity of excessive obesity, by the 

physicians of the Moorish king of Córdoba, Abderramen; but their treatment was not so harsh and sanguinary. It is certain that Juan Ventura Sarra was 

a great surgeon, and showed that he was such not only with this governor, but also in the year 1682 with his successor, Master-of-camp Don Juan Vargas 

Hurtado. There was no hope for Don Juan’s life, on account of a large abscess in the hip, which was not understood to be such by the physicians; but 

Juan Ventura knew what it was, and opened the abscess with a large lancet which he made from a dagger, more than a tercia long, since the cavity was 

very deep. In this operation he showed his skill as much as Don Juan de Vargas displayed his great bravery and endurance, which aroused admiration.
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<p>
Although the cure of Don Manuel de León was so marvelous, he did not, since that inordinate obesity was now a disease and a corruption of nature, long 

enjoy the agility and lightness of body that the medical treatment had obtained for him; and so he gradually fell back into that unusual infirmity, 

and again found himself, as before, without the use of his limbs. He had many wounds in his body, which he had received in more than fifty years of 

military life in Flandes, Alemania, and Galicia, where he had taken part in battles more celebrated than were known in those times [i.e., of which 

Diaz was writing]. He had been so courageous in not fearing dangers that they called Don Manuel de León "Ironhead." Among these he had one deep wound, 

which must have been imperfectly or only apparently healed; and this in course of time, and with the pressure on it that would be caused by the 

increase of flesh, opened, a great flow of blood issuing from it. This occurred so inopportunely that he was present in the church of Santo Domingo, 

clothed in mourning garb, assisting in the funeral rites for Doña María Cuéllar, wife of Auditor Don Francisco de Coloma. His blood flowed very 

copiously, but those near him could not see it on account of the mourning garments, and because the chair and cushion were of black, until he began to 

swoon, and sank into the chair. They carried him in their arms to his coach, and thence he was conveyed to his palace, where all the care due to the 

cure of such a personage as he was furnished. The above-mentioned Juan Ventura Sarra treated him, applying all means which the art of surgery imparts 

to those who are so skillful as was Juan Ventura, who within four months brought him to what seemed a state of convalescence. But as his age was so 

great, and could not give much aid to the medicine (which only assists nature), Don Manuel could never regain sound health. The physicians ordered him 

to go to one of the houses that stand by the river opposite Manila, where he spent a long time—until, on the night of April 8, 1676, they found him 

dead in his bed, although he had retired without any indications of such danger. They found a power of attorney authorizing the father provincial of 

St. Dominic, Master Fray Diego de San Román, to make a will in his name, and directions that he be interred in the royal chapel of the Incarnation belonging to the soldiers of Manila, where he lies in a little chapel which stands on the gospel side. He was one of the best governors who has ruled these Filipinas Islands, very disinterested, pious, affable, and clement; and his death was therefore regretted by all classes. The estate that he left was the only property belonging to a governor that was put to good use,28 the religious who acted as administrator applying it to pious works which the governor had named to him—such as the holy Bureau of La Misericordia, so that for years many orphan girls were given in marriage by means of that part [of the governor’s donation] which belonged to their dowries, until, with the successive wrecks of the two galleons "Santo Cristo de  Burgos" and "San José," in the years 1693 and 1695, the principal of that great endowment was entirely consumed. He also left directions to found a well-endowed chaplaincy in his native place—Paredes de Nava, in the district of Campos—and many other good works, worthy of his piety.
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September 24, 1669: Manuel de Leon took possession of the Philippines as new governor-general